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Rabbit anti-NCAM-1/CD56 Recombinant Monoclonal Antibody [BLR152J]
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Brand:
A700-152-T
- Brand
- Bethyl Laboratories
- Application
- ICC
IHC
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- residues 20-318 (ECD)
- Buffer
- Phosphate Buffered Saline (PBS) containing 0.2% BSA and 0.09% Sodium Azide
- Reactivity
- Human
- Target
- NCAM-1/CD56
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Recombinant Monoclonal
- Alternate Names
- antigen recognized by monoclonal antibody 5.1H11, CD antigen CD56, CD56, MSK39, NCAM, N-CAM-1, NCAM-1, neural cell adhesion molecule 1, neural cell adhesion molecule, NCAM
- Format
- Whole IgG
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:1,000
- Immunohistochemistry (IHC)
- 1:100 to 1:500. Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE tissue sections.
- Immunocytochemistry (ICC)
- 1:100 to 1:500. Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE cell sections.
- Target Sentence
- NCAM1, is a cell adhesion protein of the immunoglobulin superfamily that is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. It plays a role in the development of the nervous system by regulating neurogenesis, neurite outgrowth, and cell migration. NCAM1 is also involved in the expansion of T lymphocytes, B lymphocytes and natural killer (NK) cells which play an important role in immune surveillance. One prominent isoform NCAM1, known as cell surface molecule CD56, plays a role in several myeloproliferative disorders such as acute myeloid leukemia and differential expression of this gene is associated with differential disease progression. For example, increased expression of CD56 is correlated with lower survival in acute myeloid leukemia patients. [taken from NCBI Entrez Gene (Gene ID: 4684)].
- Product Link
- http://www.bethyl.com/product/A700-152
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